Blot verb T (DRY) to dry a wet surface, or writing done in ink, by pressing something soft against it: I signed my name and blotted the paper. She put on her lipstick and then carefully blotted her lips with a. A procedure similar to the Southern blot analysis, used to separate and identify RNA fragments; typically through transferring (blotting) RNA fragments from an agarose gel to a nitrocellulose filter followed by detection with a suitable probe. coined to distinguish it from eponymic Southern blot a. Bolts definition engineering. Blot definition is - a soiling or disfiguring mark: spot. How to use blot in a sentence. A spot or stain, especially of ink on paper. A blemish on a person's character or reputation: He had been haunted by a blot on his past. Verb (used with object), blotted, blotting. To spot, stain, soil, or the like. A spot or a stain caused by a discoloring substance: a blot of paint. An association of disgrace with one's character or reputation.
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